The ‘super’ house-mouse and the malaria carrying mosquito have made the news recently. They are just two of a growing number of pest species that are becoming less and less effected by the chemicals we use to control them. In Europe, this is quite literally a growing problem; agricultural yields are threatened by pest resistance, and regulations lack short-term solutions. The ‘super mouse’ is not a super hero, but its story may save us with the warning it carries.